Italy- Human mad cow disease reported 22 July 2010 The Sydney Morning Herald [edited] [BITES] A 42-year-old Italian woman was reported as the second ever case of mad cow disease in humans in the country and is currently hospitalized in desperate condition. The woman was diagnosed with a variant of the Creutzfeldt-Jakob disease (CJD) at a neurological hospital in the past months and was then transferred to a hospital in western Tuscany, when she was already in a coma. UK: Two cattle enter food supply breaching BSE testing regulations 30 June 2010 Food Standards Agency [edited] [BITES] The Agency has been notified that meat from two cattle, which should have been tested for BSE due to their age have entered the food supply. This is a breach of current BSE controls. One animal, born and reared in the UK, was aged 57 months and another, born in Estonia and slaughtered in the UK, was aged 37 months. BSE testing is mandatory for all UK-born cattle slaughtered for human consumption at over 48 months of age. For cattle born in some other countries, including Estonia, the testing age is at aged over 30 months By the time the failure was discovered all of the affected carcass meat and offal had left the premises. Some of the affected product had been exported to the Netherlands. The authorities in the Netherlands have been informed. Other edible products from the affected batch of animals remained in Britain. The BSE testing age for animals born in the UK was raised to 48 months at the beginning of 2009. Cattle aged over 48 months are allowed to enter the food supply provided they have tested negative for BSE. If there is no BSE test or the animal tests positive, all parts of the carcass must be condemned. Denmark- Bovine spongiform encephalopathy19 Nov 2009OIE, WAHID (World Animal Health Information Database), weekly disease information 2009; 22(47) [edited][ProMed]
SummaryReport type: immediate notification
Start date: 17 Nov 2009
Date of 1st confirmation of the event: 19 Nov 2009
Report date: 19 Nov 2009
Date submitted to OIE: 20 Nov 2009
Reason for notification: reoccurrence of a listed disease
Date of previous occurrence: September 2005
Manifestation of disease: sub-clinical infection
Causal agent: bovine spongiform encephalopathy agent
Nature of diagnosis: laboratory (advanced)
This event pertains to the whole country
New outbreaks
Total outbreaks: 1
Outbreak 1: AEroskobing, AEro Kommune, South Denmark
Date of start of the outbreak: 17 Nov 2009
Outbreak status: continuing (or date resolved not provided)
Epidemiological unit: farm
Affected animalsSpecies: cattle
Susceptible: 116
Cases: 1
Deaths: 0
Destroyed: 1
Slaughtered: 0
Affected population: the affected animal is a 14-year-old dairy cow, which was diagnosed positive for BSE on 19 Nov 2009. The cow was sent for slaughter on 16 Nov 2009 and the routine BSE test appeared positive on 17 Nov 2009. The cow originated from a herd of 116 cattle situated on the island AEro south of Funen. The cow was born in 1995 and was the oldest animal on the premises. The oldest animal present now was born in 2002, one year after the introduction of the total feed ban (see epidemiological comments).
EpidemiologySource of the outbreak(s) or origin of infection: unknown or inconclusive
Epidemiological comments: the affected animal was born before the tightening of the feed ban in 1997 and 2001. In 1990, feeding ruminant MBM to ruminants was prohibited. In 1997, feeding mammalian MBM to ruminants was prohibited. On 1 Jan 2001, the Danish Veterinary and Food Administration introduced a total ban on feeding processed animal protein (including meat and bone meal (MBM), fish meal, etc.) to animals that are kept, fattened, or bred for the production of food.
Control measuresMeasures applied: quarantine; no vaccination; no treatment of affected animals
Measures to be applied: modified stamping out
Future reportingThe event is continuing. Weekly follow-up reports will be submitted.
United Kingdom: National CJD Surveillance Unit, monthly statistics, new confirmed case of vCJD 07 Sep 2009UK National CJD Surveillance Unit, monthly statistics [edited][ProMed]
One new case of vCJD has been recorded by the CJD surveillance unit in Edinburgh. The number of deaths due to definite or probable vCJD cases now becomes 165. A total of 4 definite/probable patients remain alive, bringing the total number of definite or probable vCJD cases to 169.
Although one new case vCJE have been recorded during the past month, this is still consistent with the view that the vCJD outbreak in the UK is in decline. The 1st cases were observed in 1995, and the peak number of deaths was 28 in the year 2000, followed by 20 in 2001, 17 in 2002, 18 in 2003, 9 in 2004, 5 in 2005, 5 in 2006, 5 in 2007, one in 2008, and so far one in 2009.
As of Mon 7 Sep 2009 in the UK so far this year [2009], there have been 95 referrals, 38 cases of sporadic CJD, one case of familial CJD, one case of iatrogenic CJD, 3 cases of GSS, and one case of vCJD.
France: Institut de Veille Sanitaire- monthly statistics September- new suspected case02 Sep 2009IVS - Maladie de Creutzfeldt-Jakob et maladies apparentees [in French, trans. and summ. Mod.CP]
Since the update in the preceding month [August 2009], the previously suspected case has become a confirmed case, and another suspected case of vCJD has been identified. So far in the 1st 8 months of 2009 there have been 939 referrals, 39 cases of sporadic CJD, 7 cases of familial CJD, 2 cases of iatrogenic CJD, and one confirmed case of vCJD. There is currently one case of suspected vCJD (no details available).
United Kingdom- National CJD Surveillance Unit- monthly statistics 04 Aug 2009UK National CJD Surveillance Unit, monthly statistics [edited][ProMed]
The number of suspected cases of vCJD referred to the CJD surveillance unit in Edinburgh, and the number of deaths of definite and probable cases due to vCJD remain unchanged since the previous monthly report; that is, the number of deaths due to definite or probable vCJD cases remains 164. A total of 4 definite/probable patients remain alive, bringing the total number of definite or probable vCJD cases to 168. No cases of vCJE have been recorded during the 1st 7 months of 2009.
This situation is consistent with the view that the vCJD outbreak in the UK is in decline.
As of Tue 3 Aug 2009 in the UK so far this year [2009], there have been 80 referrals, 32 cases of sporadic CJD, one case of familial CJD, one case of iatrogenic CJD, two cases of GSS, and no cases of vCJD.
France- Institut de Veille Sanitaire- Monthly Statistics 04 Aug 2009IVS - Maladie de Creutzfeldt-Jakob et maladies apparentees [in French, trans. & summ. Mod.CP][ProMed]
Since the update in the preceding month, the suspected case of vCJD has been confirmed and a new suspected case is listed.
So far in the 1st 7 months of 2009 there have been 83 referrals, 34 cases of sporadic CJD, 6 cases of familial CJD and no case of iatrogenic CJD. There is currently one case of suspected vCJD (no details provided), and one previously unconfirmed case has now been confirmed.
July
United Kingdom- National CJD Surveillance Unit- monthly statistics 06 Jul 2009UK National CJD Surveillance Unit, monthly statistics [edited][ProMed]
The number of suspected cases of vCJD referred to the CJD surveillance unit in Edinburgh, and the number of deaths of definite and probable cases due to vCJD remain unchanged since the previous monthly report; that is, the number of deaths due to definite or probable vCJD cases remains 164. Four definite/probable patients remain alive, bringing the total number of definite or probable vCJD cases to 168. No cases of vCJE have been recorded during the 1st 6 months of 2009.
This situation is consistent with the view that the vCJD outbreak in the UK is in decline. The 1st cases were observed in 1995, and the peak number of deaths was 28 in the year 2000, followed by 20 in 2001, 17 in 2002, 18 in 2003, 9 in 2004, 5 in 2005, 5 in 2006, 5 in 2007, only one in 2008, and none so far in 2009.
France- Institut de Veille Sanitaire- monthly statistics01 Jul 2009IVS - Maladie de Creutzfeldt-Jakob et maladies apparentees [in French, trans. & summ. Mod.CP, edited][ProMed]
So far in the 1st 6 months of 2009, there have been 731 referrals, 29 cases of sporadic CJD, 5 cases of familial CJD and no case of iatrogenic CJD. There is currently one case of suspected vCJD (no details provided), but no confirmed case of vCJD.
June
France - Monthly statistics 02 Jun 2009IVS - Maladie de Creutzfeldt-Jakob et maladies apparentees[in French, trans. & summ. Mod.CP, edited][ProMed]
So far in 2009 there have been 609 referrals, 23 cases of sporadic CJD, 4 cases of familial CJD and no cases of iatrogenic CJD. There is currently one case of suspected vCJD (no details provided), but no confirmed case of vCJD.
In total there have been 23 cases of confirmed or probable vCJD in France, since 1992 when records began, and currently there is one case pending.
Twelve of the confirmed cases have been male, and 11 female. The median age is 34 years (range 19 to 58 years.
United Kingdom National CJD Surveillance Unit-monthly statistics 1 Jun 2009UK National CJD Surveillance Unit, monthly statistics [edited][ProMed]
The number of suspected cases of vCJD referred to the CJD surveillance unit in Edinburgh, and the number of deaths of definite and probable cases due to vCJD remain unchanged since the previous monthly report; that is, the number of deaths due to definite or probable vCJD cases remains 164. Four definite/probable patients remain alive, bringing the total number of definite or probable vCJD cases to 168.
This situation is consistent with the view that the vCJD outbreak in the UK is in decline. The 1st cases were observed in 1995, and the peak number of deaths was 28 in the year 2000, followed by 20 in 2001, 17 in 2002, 18 in 2003, 9 in 2004, 5 in 2005, 5 in 2006, 5 in 2007, only one in 2008, and none so far in 2009.
As of Mon 1 Jun 2009 in the UK so far this year [2009], there have
been 52 referrals, 21 cases of sporadic CJD, one case of familial
CJD, one case of iatrogenic CJD, and no cases of GSS or vCJD.
April
United Kingdom - National CJD Surveillance Unit - monthly statistics as of 6 Apr 2009
6 Apr 2009
UK National CJD Surveillance Unit, monthly statistics [edited] [Promed]
The number of suspect cases of vCJD referred to the CJD surveillance unit in Edinburgh, and the number of deaths of definite and probable due to vCJD remain unchanged since the previous monthly report; that is, the number of deaths due to definite or probable vCJD cases remains 164. Four definite/probable patients remain alive, bringing the total number of definite or probable vCJD cases to 168.
This situation is consistent with the view that the vCJD outbreak in the UK is in decline. The 1st cases were observed in 1995, and the peak number of deaths was 28 in the year 2000, followed by 20 in 2001, 17 in 2002, 18 in 2003, 9 in 2004, 5 in 2005, 5 in 2006, 5 in 2007, only one in 2008, and none so far in 2009.
Totals for all types of CJD cases in the UK in 2009As of Mon 6 Apr 2009 in the UK so far this year [2009], there have been 28 referrals, 11 cases of sporadic CJD, one case of familial CJD, one case of iatrogenic CJD, and no cases of GSS or vCJD.
France - Institut de Veille Sanitaire - as of 1 Apr 2009
1 Apr 2009
IVS - Maladie de Creutzfeldt-Jakob et maladies apparentees [in French, trans. & summ. Mod.CP, edited] [Promed]
During the period 1 Jan 2009 to 1 Apr 2009 there were 359 referrals, 12 cases of sporadic CJD, 1 case of familial CJD, no cases of iatrogenic CJD, and no cases of vCJD. [With more than 10 times the number of referrals, the numbers with final diagnoses are remarkably similar to those recorded in the UK during the same period. - Mod.CP/JW]
During the period 1992 to 2008, there were 23 cases of vCJD, all now deceased. They occurred between 1996 and 2007: one case in 1996, one in 2000, one in 2001, 3 in 2002, none in 2003, 2 in 2004, 6 in 2005, 6 in 2006, 3 in 2007, none in 2008, and none so far in 2009. There were 12 male and 11 female patients.
March
Spain - Suspected case of vCJD
29 Mar 2009
CNN International Health News [edited] [Promed]
According to this story, a Spanish pathologist who specialized in a human strain of mad cow disease died Saturday [28 Mar 2009], and officials suspect the disease played a role in his death. It is reported that the doctor was head of the anatomy pathology section at the University Hospital Principe de Asturias in Alcala de Henares. Several samples have been sent off for testing, the office said, but results are expected to take a month. It is not known how the doctor might have contracted the disease, but the health office said it was not thought to be through ingestion of contaminated meat. The story goes on by explaining that authorities are investigating whether the doctor had been exposed to contaminated human tissue through his work.
Czech Republic – New case of bovine spongiform encephalopathy (BSE) 28 Mar 2009
Pandemic Information News [edited] [Promed]
Czech state veterinarians said on Friday [27 Mar 2009] they had found a new case of bovine spongiform encephalopathy (BSE) in a 6-year-old cow on a farm near the northern border with Poland.
Spain reports fifth human death from mad cow disease 06 Mar 2009
AFP [edited][iFSN]
It is reported that the Spanish government late Friday confirmed the country's fifth fatality from the human variant of mad cow disease, a woman who died in the northern city of Santander in January. The health ministry said laboratory tests confirmed that the woman had Creutzfeldt-Jakob Disease (CJD) as the human variant of bovine spongiform encephalopathy (BSE), or mad cow disease, is known.
Related stories 7 Mar 2009 -
Woman dies from mad cow disease in Spain CNN International
United Kingdom - National CJD Surveillance Unit - monthly statistics as of 2 Mar 2009
2 Mar 2009
UK National CJD Surveillance Unit, monthly statistics [edited] [Promed]
The number of suspect cases of vCJD referred to the CJD surveillance unit in Edinburgh and the number of deaths of definite and probable variant Creutzfeldt-Jakob disease [abbreviated in ProMED-mail as CJD (new var.) or vCJD], the form of the disease thought to be linked to BSE (bovine spongiform encephalopathy), remain unchanged since the previous monthly report; that is, the number of definite or probable vCJD cases remains 164. Four definite/probable patients remain alive, bringing the total number of definite or probable vCJD cases to 168.
This situation is consistent with the view that the vCJD outbreak in the UK is in decline. The 1st cases were observed in 1995, and the peak number of deaths was 28 in the year 2000, followed by 20 in 2001, 17 in 2002, 18 in 2003, 9 in 2004, 5 in 2005, 5 in 2006, 5 in 2007, only one in 2008, and none so far in 2009.
Totals for all types of CJD cases in the year 2009
As of Mon 2 Mar 2009 in the UK so far this year [2009], there have been 14 referrals, 3 cases of sporadic CJD, one case of familial CJD, one case of iatrogenic CJD, and no cases of GSS or vCJD.
February
United Kingdom -Council leader dies from human form of mad cow disease 20 Feb 2009
Telegraph.co.uk Bob Austin, who left Cotswold District Council in July last year, was just 56 when he died on Thursday. Doctors diagnosed him with suspected Creutzfeldt-Jakob disease, which causes severe brain damage, just months before. However, it cannot be 100 percent confirmed if a person has died from the illness until after a post mortem examination.
United Kingdom - Cow aged over 30 months enters food supply without being tested for BSE 05 Feb 2009
Food Standards Agency [edited Promed]
The Agency has been notified that a heifer aged two days over thirty months has entered the food supply without having been tested for BSE.
At the time this occurred, BSE testing was mandatory for cattle slaughtered for human consumption at over thirty months of age (since the beginning of this year, the BSE testing age has been raised to 48 months).
However, as specified risk material (SRM) was removed from the animal, and it is unlikely that the animal was infected with BSE, any risk to human health is very low. SRM is those parts of the animal that contain almost all BSE infectivity, if the animal is infected with BSE.
The heifer was slaughtered on 17 November 2008 at Higginshaw Abattoir (trading as Samuel Howarth Ltd) in Oldham, Greater Manchester.
The error was discovered on 14 January 2009 during routine cross checks of slaughter and BSE test data. By then, all the affected meat and offal had left the slaughterhouse. Subsequent checks indicate that all the product remained within the UK and is likely to have been consumed.
Since the beginning of this year, the BSE testing age has been raised to 48 months. Cattle aged over 48 months are allowed to enter the food supply provided they have tested negative for BSE. If there is no BSE test, all parts of the carcass must be condemned.
Specified risk material (SRM) is those parts of the animal that contain almost all BSE infectivity, if the animal is infected with BSE. SRM includes the vertebral column of cattle aged over thirty months.
Netherlands - 3rd vCJD death
2 Feb 2009
AFP/Expatica [edited Promed]
It is reported that a 3rd person in the Netherlands died of the human variant of mad cow disease, Creutzfeldt-Jakob (vCJD), at the beginning of January 2009. According to this story, the national health research agency RIVM said on Monday that "The patient died at the beginning of January [2009]" and that "An investigation has confirmed that the patient died of the variant form of Creutzfeldt-Jakob disease." The RIVM did not say how, when or where the patient contracted the disease but pointed out that the incubation period, from infection to the display of symptoms, could last decades. Investigations were ongoing into the "very rare chance" that the patient may have infected other people. The statement stressed that Dutch beef was safe, explaining that all slaughtered cows are tested for BSE since 2001.
United Kingdom - National CJD Surveillance Unit - monthly statistics as of 2 Feb 2009
2 Feb 2009
UK National CJD Surveillance Unit, monthly statistics [edited] [Promed]
The number of suspect cases of vCJD referred to the CJD surveillance unit in Edinburgh, and the number of deaths of definite and probable variant Creutzfeldt-Jakob disease [abbreviated in ProMED-mail as CJD (new var.) or vCJD], the form of the disease thought to be linked to BSE (bovine spongiform encephalopathy), remain unchanged since the previous monthly report; that is, the number of definite or probable vCJD cases (dead and alive) remains 167.
This situation is consistent with the view that the vCJD outbreak in the UK is in decline. The 1st cases were observed in 1995, and the peak number of deaths was 28 in the year 2000, followed by 20 in 2001, 17 in 2002, 18 in 2003, 9 in 2004, 5 in 2005, 5 in 2006, 5 in 2007, only one in 2008, and none so far in 2009.
Totals for all types of CJD cases in the year 2009
As of Mon 2 Feb 2009 in the UK, so far this year [2009], there have been 2 referrals and no cases of sporadic, iatrogenic, familial, or variant CJD, or GSS.
January
France - Institut de Veille Sanitaire - as of 30 Jan 2009
30 Jan 2009
IVS - Maladie de Creutzfeldt-Jakob et maladies apparentees [French, trans. & summ. Mod.CP, edited] [Promed]
During the period 1992 to 2008, there were 23 cases of vCJD, all now deceased. They occurred between 1996 and 2007: One case in 1996, one in 2000, one in 2001, 3 in 2002, none in 2003, 2 in 2004, 6 in 2005, 6 in 2006, 3 in 2007, and none so far in 2008. There were 12 male and 11 female patients.
Their ages at time of death ranged from 19 to 58 years (mean 39); 6 of the patients resided in the Ile-de-France [Paris area] and 17 in the provinces. All the cases were met-met homozygotes for codon 129 of the prion protein gene. No special risk factors were evident, which distinguished these patients from those with other forms of CJD (sporadic, genetic, iatrogenic). However, one patient had visited the UK at regular intervals.
Totals for all types of CJD cases in the year 2008
As of 30 Dec 2008 in France, during the course of 2008, there have been 1438 referrals, 76 deaths from sporadic CJD, 3 deaths from iatrogenic CJD, 8 from familial CJD, none from GSS, and none from vCJD.
As of 30 Jan 2009, 106 cases were referred with no CJD diagnoses recorded.
Spain- BSE 9 Jan 2009 ThinkSpain [edited] [Promed]
According to this story, the regional Environment Ministry for Madrid has issued a statement to report that a 10-year-old cow from a farm in Galapagar diagnosed with bovine spongiform encephalopathy (BSE) on 29 Dec 2008 has been put down at a local slaughterhouse. There have been 6 confirmed cases of the disease since 2000 in the Madrid region, the last being in 2004. Last year [2008], 10,000 inspections were carried out in the region, where there are around 4800 cattle farms. It is reported that the ministry gave assurances that measures are already in place which ensure that this last case does not constitute any kind of risk to the food chain.
UK: National CJD Surveillance Unit - monthly statistics as of 5 Jan 2009
5 Jan 2009
UK National CJD Surveillance Unit [edited] [Promed]
The number of suspect cases of vCJD referred to the CJD surveillance unit in Edinburgh and the number of deaths of definite and probable variant Creutzfeldt-Jakob disease, the form of the disease thought to be linked to BSE (bovine spongiform encephalopathy), remain unchanged since the previous monthly report; that is, the number of definite or probable vCJD cases (dead and alive) remains 167.
This situation is consistent with the view that the vCJD outbreak in the UK is in decline. The first cases were observed in 1995, and the peak number of deaths was 28 in the year 2000, followed by 20 in 2001, 17 in 2002, 18 in 2003, 9 in 2004, 5 in 2005, 5 in 2006, 5 in 2007, and only one so far (up to the end of 2008).
Totals for all types of CJD cases in the year 2008
As of 31 Dec 2008 in the UK, so far there have been 140 referrals, 73 deaths from sporadic CJD, 5 deaths from iatrogenic CJD, 3 from GSS, 2 from familial CJD, and one from vCJD.
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