Peru- Risk factors for antibiotic-resistant Escherichia coli carriage in young children: Community-based cross-sectional prevalence study01 May 2010
Am. J. Trop. Med. Hyg., 82(5), 2010, pp. 879-888 [edited][FSNet]
Henry D. Kalter, Robert H. Gilman, Lawrence H. Moulton, et al.
Few studies have examined the influence of individual-, household-, and community-scale risk factors on carriage of resistant commensal bacteria. We determined children's medical, agricultural, and environmental exposures by household, pharmacy, and health facility surveys and
Escherichia coli cultures of children, mothers' hands, household animals, and market chickens in Peru. Among 522 children with a positive stool culture, by log-binomial regression, using "any antibiotic" and 1–14 (versus 0) sulfa doses in the past 3 months increased children's risk, respectively, for ampicillin- and sulfamethoxazole-resistant E. coli carriage (P = 0.01–0.02). Each household member taking "any antibiotic" increased children's risk for sulfamethoxazole- and multidrug-resistant
E. coli carriage.